Ancylostoma caninum, also known as the hookworm, is a parasitic nematode that infects dogs and other canines. It's a common problem worldwide, especially in tropical and subtropical regions.
Ancylostoma caninum is a type of intestinal parasite that attaches to the host's intestinal wall, feeding on blood and nutrients. It's usually spread through contaminated soil, feces, or the bites of infected fleas.
These hookworms can cause anemia, weight loss, and diarrhea in infected dogs. In severe cases, it can lead to organ failure and even death.
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What is Ancylostoma Caninum?
Ancylostoma caninum is a type of parasitic worm that affects dogs and foxes.
It's primarily spread through the ingestion of L3 larvae from the environment, or by percutaneous infection of larvae, which means they enter the body through the skin.
The pre-patent period, or the time before symptoms appear, is around 2-3 weeks.
During this time, the larvae are developing inside the host, and the immune system is fighting off the infection.
Symptoms can be acute or chronic and include diarrhoea, bloody diarrhoea, weight loss, and anaemia.
Egg detection is possible through flotation from 3-5g of fresh or fixed faeces.
Coproantigen assays can also detect infections from immature and adult worms, making it possible to identify infections during the pre-patent period.
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Laboratory Safety
When working with stool specimens or larval cultures, it's essential to wear appropriate PPE, such as gloves and a gown, to minimize the risk of transdermal penetration.
Ethanol is a suitable surface disinfectant for killing hookworm larvae, as it can kill 95.6% of infective N. americanus larvae within five minutes and all such larvae within 10 minutes.
Lugol's iodine, specifically 1% povidine iodine or 10,000 ppm, is also effective in killing hookworm larvae on exposed skin.
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Life Cycle and Development
Ancylostoma caninum, also known as the dog hookworm, has a fascinating life cycle that's worth exploring.
The eggs of Ancylostoma caninum hatch into the first-stage juvenile in the soil in approximately one day.
In an environment of 23 degrees Celsius, the egg hatches into the first-stage juvenile in the soil in approximately one day.
The larvae grow in the feces and/or the soil, and after 5 to 10 days, they become filariform (third-stage) larvae that are infective.
These infective larvae can survive 3 to 4 weeks in favorable environmental conditions.
Infection of the host can occur through ingestion or by penetration of the unbroken skin, but either way, the parasite ends up in the small intestine of the host.
The adult worms live in the lumen of the small intestine, where they attach to the intestinal wall.
Copulation occurs within the small intestine and the female worms pass eggs in the feces.
Transplacental and transmammary transmission are known for dogs infected with Ancylostoma caninum.
Occasionally, an Ancylostoma caninum juvenile will penetrate the skin of a human but cannot complete its life cycle in the inappropriate host.
The juvenile wanders about in the upper layers of the skin, causing a condition called dermal larva migrans.
Hosts and Habitat
Ancylostoma caninum, the common hookworm, has a fascinating host and habitat profile. Canids such as domestic dogs, wolves, coyotes, and foxes are its primary hosts. Ancylostoma caninum is also found in felids and cattle, but only the cattle-associated species (B. phlebotomum) has been definitively shown to infect humans.
The hookworm's habitat is quite diverse, ranging from temperate to tropical regions, and including terrestrial biomes such as desert or dune, savanna or grassland, chaparral, forest, rainforest, scrub forest, and mountains. Temperature also plays a crucial role in the hookworm's life cycle, with optimal conditions found in temperate and warm climates.
Here's a breakdown of the hookworm's geographical distribution:
- Temperate and tropical regions in Australia, New Zealand, Tasmania, New Guinea, and associated islands.
- Central and South America in the southern part of the New World.
- Europe, Asia, and northern Africa in the northern part of the Old World.
- The oriental region, including India and southeast Asia.
Hosts
Canids such as domestic dogs, wolves, coyotes, and foxes are the primary hosts for Ancylostoma caninum. They're common carriers of this parasite.
Ancylostoma braziliense and Uncinaria stenocephala can also be found in felids, in addition to canids.
Bunostomum spp. infect sheep, goats, and cattle, but only the cattle-associated species (B. phlebotomum) has been definitively shown to infect humans.
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Habitat
Ancylostoma caninum is found in various habitats around the world. It thrives in temperate and tropical climates.
The parasite is commonly found in terrestrial biomes, including deserts or dunes, savannas or grasslands, chaparral, forests, rainforests, scrub forests, and mountains.
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In terms of geographical distribution, Ancylostoma caninum is found in Australia, New Zealand, Tasmania, New Guinea, and associated islands, as well as in the southern part of the New World, which includes Central and South America.
It's also present in the northern part of the Old World, covering Europe, Asia, and northern Africa.
The parasite's body temperature is ectothermic, meaning it fluctuates with the environment's temperature.
Geographic and Distributional Information
Ancylostoma caninum, also known as the dog hookworm, is a parasite that's found all over the world. It's broadly distributed in wild and domestic canids and felids, meaning it's common in dogs and cats.
The geographic distribution of Ancylostoma caninum is truly global, with the parasite found in warm and temperate climates. This includes regions like the southeastern United States, Latin America, South America, Africa, and even parts of Australia and New Zealand.
Ancylostoma caninum is a cosmopolitan parasite, meaning it's found in many different parts of the world. It thrives in areas with adequate moisture, which is why it's so common in tropical and subtropical regions.
Here are some of the biogeographic regions where Ancylostoma caninum has been found:
- nearctic
- palearctic
- oriental
- ethiopian
- neotropical
- australian
The parasite's life cycle begins in the soil, where the first larval stage molts twice before emerging into its infectious third stage.
Clinical Presentation and Diagnosis
Cutaneous larva migrans is the most common manifestation of zoonotic infection with animal hookworm species. It's characterized by intensely pruritic and erythematous serpiginous tracks in the upper dermis.
These tracks can spread up to a few centimeters daily, and secondary infections can develop following excessive scratching. In some cases, the larvae can even migrate to the eye, causing diffuse unilateral subacute retinitis.
Infective third-stage larvae are 500–600 µm long, with a pointed tail and a striated sheath. They're found in the environment and infect the human host by penetration of the skin.
Clinical Presentation
Cutaneous larva migrans (CLM) is a common manifestation of zoonotic infection with animal hookworm species. It's characterized by intensely pruritic and erythematous serpiginous tracks in the upper dermis.
These tracks can spread up to a few centimeters daily, making it essential to manage excessive scratching to prevent secondary infections.
In some cases, diffuse unilateral subacute retinitis can occur, where a single larvae compatible in size with Ancylostoma spp. is visualized in the affected eye.
Infective, third-stage (L3), filariform larvae are 500–600 µm long and have a pointed tail and a striated sheath. They're found in the environment and infect the human host by penetration of the skin.
Adults of CLM-causing hookworm species are typically found in canid and felid hosts, measuring approximately 8–12 mm long in males and 10–15 mm long in females.
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Diagnosis
Diagnosis is a critical step in understanding and treating a condition. A thorough medical history, including questions about symptoms, lifestyle, and medical history, is essential for diagnosis.
The healthcare provider will ask questions to determine the severity and duration of symptoms, as well as any factors that may have triggered them. This information helps narrow down possible causes.
A physical examination is also necessary to observe any visible signs or abnormalities. This may involve checking vital signs, such as heart rate and blood pressure.
The healthcare provider may order diagnostic tests, such as blood work or imaging studies, to confirm a diagnosis. These tests can help identify underlying conditions or rule out potential causes.
The results of diagnostic tests are reviewed and considered alongside the medical history and physical examination to confirm a diagnosis. This comprehensive approach ensures an accurate diagnosis and effective treatment plan.
Classification and Causative Organisms
Ancylostoma caninum, commonly known as the dog hookworm, is a parasitic worm that primarily infects canines. It's a relatively large worm, measuring 8-11 mm in length.
This species of hookworm is a member of the Ancylostomidae family and belongs to the genus Ancylostoma. The classification of Ancylostoma caninum is as follows:
- Kingdom: Animalia
- Phylum: Nematoda
- Class: Secernentea
- Order: Strongylida
- Family: Ancylostomidae
- Genus: Ancylostoma
- Species: Ancylostoma caninum
Ancylostoma caninum is known to cause eosinophilic enteritis in humans, although it also causes cutaneous larva migrans in a minority of cases.
Common Name
The common name of a disease can be quite misleading, as it often doesn't reflect the actual causative organism.
For example, the disease known as "ringworm" is not caused by a worm at all, but by a fungus called Trichophyton.
Diseases like "athlete's foot" and "jock itch" are also caused by fungi, specifically Trichophyton and Epidermophyton, respectively.
These fungi thrive in warm, moist environments, which is why they're commonly found in locker rooms and showers.
Scientific Name
The scientific name of a species is a unique identifier that consists of two parts: a genus name and a species name.
The genus name is always capitalized and is a noun that represents the group of organisms to which the species belongs.
For example, the scientific name of the bacterium that causes tuberculosis is Mycobacterium tuberculosis.
Classification
Classification is a crucial step in understanding the world around us, and in the context of causative organisms, it's essential to get it right. The kingdom Animalia is the broadest classification, encompassing all animals.
Animalia is further divided into phyla, one of which is Nematoda, which includes roundworms. These worms have a relatively simple body structure, with only a few thousand species described.
Within the class Secernentea, we find the order Strongylida, which includes parasitic worms like hookworms. The family Ancylostomidae is a specific group within this order, and it's here that we find the genus Ancylostoma.
Ancylostoma caninum is a specific species of hookworm that affects dogs. This species has been extensively studied and documented, with a wealth of information available online.
Here's a breakdown of the classification hierarchy for Ancylostoma caninum:
- Kingdom: Animalia
- Phylum: Nematoda
- Class: Secernentea
- Order: Strongylida
- Family: Ancylostomidae
- Genus: Ancylostoma
- Species: Ancylostoma caninum
Causative Organisms
Necator americanus is the globally predominant human hookworm, a small, cylindrical, off-white worm that measures 7-9 mm in length for adult males and 9-11 mm for adult females.
Ancylostoma duodenale, another causative organism, is more geographically restricted and primarily infects humans, causing classic hookworm disease.
It can live in the small intestines of cats and dogs, but adult males of this species measure 8-11 mm and adult females measure 10-13 mm.
Necator americanus can be differentiated from Ancylostoma duodenale on the basis of the cutting plates it possesses in place of teeth.
Here's a list of the causative organisms mentioned:
- Necator americanus
- Ancylostoma duodenale
- Ancylostoma ceylanicum
- Ancylostoma caninum
- Ancylostoma braziliense
Ancylostoma ceylanicum primarily infects canines and felines, but can cause milder classic hookworm disease in humans.
Ancylostoma braziliense is a canine and feline hookworm that causes cutaneous larva migrans, or creeping eruption, a self-limiting condition in humans.
Frequently Asked Questions
How is Ancylostoma caninum transmitted to humans?
Ancylostoma caninum is transmitted to humans through skin contact with contaminated feces or soil, where the hookworm larvae penetrate and migrate through the skin. This usually occurs when humans walk barefoot or come into contact with contaminated soil or sand.
Is Ancylostoma a pinworm?
No, Ancylostoma is not a type of pinworm. It's actually a genus of hookworms that feed on human blood and cause hookworm disease.
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