Canine Heart Cancer: Prevention and Early Detection Strategies

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Posted Oct 20, 2024

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A Variety of Cancer Awareness Ribbons
Credit: pexels.com, A Variety of Cancer Awareness Ribbons

Canine heart cancer is a serious and often misunderstood condition. According to the article, it's the second most common form of cancer in dogs, after skin cancer.

The risk factors for canine heart cancer include breed, with certain breeds like the Boxer and Doberman Pinscher being more prone to the disease.

Maintaining a healthy weight through regular exercise and a balanced diet can help reduce the risk of heart cancer in dogs.

Heart health can also be improved by limiting exposure to environmental toxins and pollutants, as these can increase the risk of heart cancer.

Consider reading: Heart Murmur in Chihuahuas

What Is Canine Heart Cancer?

Canine heart cancer is a serious and often misunderstood disease.

It's the second most common type of cancer in dogs, after skin cancer.

Heart cancer in dogs typically occurs in the heart muscle, which is called myocardium.

The most common type of canine heart cancer is called hemangiosarcoma, a malignant tumor that originates from blood vessel cells.

This type of cancer is aggressive and can spread quickly to other parts of the body.

Symptoms of canine heart cancer may include difficulty breathing, lethargy, and a poor appetite.

As the disease progresses, dogs may experience more severe symptoms such as fainting and collapse.

Here's an interesting read: Canine Lupus

Causes and Risk Factors

Credit: youtube.com, Hemangiosarcoma (HSA) In Dogs

Canine heart cancer, also known as hemangiosarcoma, has a genetic component, with certain breeds being more susceptible.

Golden Retrievers, Portuguese Water Dogs, Boxers, and German Shepherd Dogs are considered to be at higher risk.

The age of a dog also plays a role, with senior dogs between 8 and 12 years being more commonly diagnosed.

Dogs as young as 2 and as old as 15 have been diagnosed with HSA, showing that it can affect dogs of any age.

The reason behind this susceptibility is still unknown, but it's worth noting that HSA is very rarely seen in livestock like horses, cows, and goats.

Symptoms and Diagnosis

Symptoms of canine heart cancer can be subtle and may not be immediately apparent. Many dogs with hemangiosarcoma, a common type of heart cancer in dogs, don't show any symptoms for a long time.

Some dogs may exhibit symptoms such as depression, refusal to walk or play, pale gums, trouble breathing, collapse, and a distended abdomen, especially if the tumor ruptures and causes internal bleeding.

Intriguing read: Heart Attack

Credit: youtube.com, Hemangiosarcoma Dog Symptoms: What Happens in the Last Days | Dr. Trina Hazzah Q&A

A veterinarian should obtain a thorough patient history and perform a complete physical examination to diagnose hemangiosarcoma. They may recommend blood tests, such as a complete blood count, serum biochemical profile, and coagulation profile, to evaluate the dog's blood cell numbers, organ function, and blood clotting ability.

Here are some common diagnostic tests used to diagnose hemangiosarcoma:

  • Complete blood count
  • Serum biochemical profile
  • Coagulation profile
  • Chest radiography (x-rays)
  • Abdominal radiography +/- sonography
  • Echocardiography

Symptoms

Hemangiosarcoma can be a sneaky disease, and many dogs don't show any symptoms for a long time.

Many dogs with HSA don't show any symptoms for a long time, which can make it difficult to diagnose.

HSA isn't painful, so if your dog has no anemia, he can seem quite normal.

This means that you should be aware of your dog's overall health and behavior, rather than just looking for obvious signs of illness.

Diagnosis Methods

Any skin mass larger than a pea (1 cm) and/or any that has been present for more than one month should be evaluated by a veterinarian.

Dog Getting a Check Up
Credit: pexels.com, Dog Getting a Check Up

To determine the type of growth, a veterinarian will aspirate some cells from the mass(es). This is because no one, not even a veterinarian, can simply look at a skin mass and know what it is.

A thorough patient history and complete physical examination are essential for diagnosing hemangiosarcoma. This helps veterinarians identify potential symptoms and signs of the disease.

Some initial blood and urine tests, as well as diagnostic imaging, will be recommended. These include:

  • Complete blood count – a non-invasive blood test that measures red blood cells, white blood cells, and platelets
  • Serum biochemical profile – a non-invasive blood test that assesses liver and kidney function, as well as electrolytes (i.e.: sodium and potassium) and certain gastrointestinal enzymes.
  • Urinalysis – non-invasive urine test that helps to evaluate renal function and to screen for possible urinary tract inflammation and infection.
  • Coagulation profile – a non-invasive blood test helps determine if a patient can properly form a proper blood clot
  • Chest radiography (x-rays) – a non-invasive imaging test to screening for evidence of heart and lung changes, including metastasis (cancer spread)
  • Abdominal radiography +/- sonography – non-invasive imaging of the abdomen can assess organ size and architecture, and identify tumors of internal organs
  • Echocardiography – Sonographic examination of the heart can evaluate this organ’s function, identify tumors of the heart, and confirm the presence of abnormal fluid in the sac around the heart (called pericardial effusion) caused by a bleeding tumor

A definitive diagnosis of hemangiosarcoma is made by removal and biopsy of the tumor.

Treatment and Management

Surgery is the primary method of treatment for most dogs with hemangiosarcoma, regardless of the location of the primary tumor.

Chemotherapy delivered after surgery may delay metastasis, and standard chemotherapy typically consists of the drug doxorubicin given once every 2-3 weeks for a total of five treatments.

The prognosis for dogs with hemangiosarcoma is generally poor, with average survival times with surgery and chemotherapy being approximately 5-7 months.

Credit: youtube.com, Heart Tumors in Dogs | Wag!

Only 10% of dogs survive for one year despite treatment.

Dogs with the subcutaneous form of hemangiosarcoma may do somewhat better than the average survival time.

Surgical removal of the tumor is often curative for dermal hemangiosarcoma, with a reported median survival time of 780 days.

However, complete excision is not often possible for subcutaneous hemangiosarcoma, and patients may benefit from chemotherapy and/or radiation therapy.

Visceral hemangiosarcoma requires aggressive therapies, including emergency surgery for bleeding masses in internal organs.

The median survival time for dogs with splenic hemangiosarcoma treated only with surgery is 19-86 days, but chemotherapy after surgery is often recommended.

Use of the drug doxorubicin is associated with longer survival times, with reported median survival times of 141-179 days for splenic hemangiosarcoma treated with surgery and doxorubicin-based chemotherapy.

Prevention and Supplements

Light-skinned or thin-coated dogs susceptible to skin hemangiosarcoma should avoid a lot of sun exposure. This can help prevent the disease.

Managing a dog's healthy lifestyle is crucial in preventing hemangiosarcoma. Being meticulous about their lifestyle can make a big difference.

Credit: youtube.com, Supplements for Dogs with Cancer | Dr. Demian Dressler Deep Dive

Research suggests that medicinal mushrooms, specifically turkey tail mushrooms, can extend a dog's survival time with hemangiosarcoma. They've been proven to double a dog's survival time in some cases.

Turkey tail mushrooms contain a compound called polysaccharopeptide (PSP), which has been shown to have a significant impact on hemangiosarcoma. A study found that dogs treated with PSP from turkey tail mushrooms lived longer than a year with no further treatment.

Preventing Cancer

Reducing sun exposure is crucial for light skinned or thin coated dogs susceptible to skin HSA.

Neutering can increase the risk of developing hemangiosarcoma in dogs. According to a study, Vizslas that were neutered were more likely to develop cancer and behavioral disorders.

A study of 217 cases found that splenic hemangiosarcoma and splenic hematoma in dogs are often associated with painless symptoms. However, the prognosis for these cases is generally poor.

Neutering is associated with developing hemangiosarcoma in dogs, according to a study that matched cases with controls. This suggests that neutering may be a contributing factor to the development of this cancer.

A whole body computed tomographic study found that dogs with hemangiosarcoma often develop skeletal muscle metastases. This can lead to a poor prognosis for affected dogs.

Some natural solutions may help manage hemangiosarcoma and improve quality of life for dogs with this cancer.

If this caught your attention, see: Canine Cancer Prognosis

Supplements That Help

Veterinarian Checking the Ear of a Dog Using Surgical Scissors
Credit: pexels.com, Veterinarian Checking the Ear of a Dog Using Surgical Scissors

Medicinal mushrooms are a top supplement to consider for dogs with hemangiosarcoma.

Turkey tail mushrooms, specifically, have been shown to extend a dog's survival time with hemangiosarcoma.

Research has proven that extra turkey tail mushrooms are beneficial, even if they're already included in a mushroom supplement blend.

A 2012 study at the University of Pennsylvania treated hemangiosarcoma dogs with an extract of polysaccharopeptide (PSP) from turkey tail mushrooms.

The median survival time in the 100 mg group was the highest, at 199 days, which is more than double the previous report of 86 days.

Doxorubicin chemotherapy, which is often used to treat hemangiosarcoma, has a median survival time of 141 to 179 days, without the side effects or huge expense of treatment.

Yunnan Baiyo is a popular herbal formula in Traditional Chinese Veterinary Medicine (TCVM) that may be beneficial for dogs with hemangiosarcoma, although its exact ingredients are not publicly available.

Early Detection Research

Early detection is crucial in treating canine heart cancer, specifically hemangiosarcoma. Research is being conducted to identify new diagnostic tests that can catch HSA at an earlier stage.

Credit: youtube.com, Hemangiosarcoma Research Findings (Part 1)

The Cornell's Coonrod Lab is working on developing ways to identify HSA and differentiate it from non-life-threatening conditions, making earlier detection possible. This could help dog owners make more informed decisions about treatments.

Tufts Cummings School of Veterinary Medicine is researching a blood test for early detection and is also working to identify genetic changes that may drive resistance to therapy. This could lead to more effective treatment options.

A clinical trial at the University of Pennsylvania School of Veterinary Medicine is examining the safety and efficacy of a chemotherapy drug called Copanlisib. This could potentially slow the growth and spread of canine cancers.

The Morris Animal Foundation is conducting a lifetime study of Golden Retrievers to investigate risk factors for cancer, including hemangiosarcoma. After 10 years of research, data shows that 75% of study dogs' deaths are cancer-related, with almost 70% of those cancer deaths being due to hemangiosarcoma.

Researchers are working to develop a simple and reliable test that can predict the risk of dogs developing hemangiosarcoma, as well as other types of cancer. The Shine On Project at the University of Minnesota College of Veterinary Medicine is leading this research effort.

Related reading: Canine Cancer Detection

Credit: youtube.com, Early Detection and Strategic Prevention of Canine Hemangiosarcoma

Here are some of the research projects mentioned above:

  • Cornell's Coonrod Lab: Developing new diagnostic tests for HSA
  • Tufts Cummings School of Veterinary Medicine: Researching a blood test for early detection and identifying genetic changes
  • University of Pennsylvania School of Veterinary Medicine: Examining the safety and efficacy of Copanlisib
  • Shine On Project: Developing a simple and reliable test to predict cancer risk
  • Morris Animal Foundation: Conducting a lifetime study of Golden Retrievers to investigate cancer risk factors

General Information

Canine heart cancer is a serious and often misunderstood condition. It's the second most common type of cancer in dogs, after skin cancer.

Dogs over the age of 10 are more likely to develop heart cancer, with some breeds such as Golden Retrievers and German Shepherds being at higher risk.

Heart cancer in dogs can be caused by a variety of factors, including genetics, environmental toxins, and lifestyle choices.

Frequently Asked Questions

How long can a dog live with cancer of the heart?

Unfortunately, the average survival time for dogs with heart cancer is short, ranging from 1-7 months with treatment, and nearly all dogs pass away within 2 years. Learn more about the prognosis and treatment options for canine heart cancer

How long will a dog live with hemangiosarcoma without surgery?

Without treatment, a dog with hemangiosarcoma typically lives 1-2 weeks, but some may survive several months. Prompt veterinary care is crucial for improving prognosis and survival time.

What is the life expectancy of a dog with adenocarcinoma?

Life expectancy for dogs with adenocarcinoma is typically less than 12 months from diagnosis. However, with proper care and treatment, their quality of life can be improved during this time.

Sources

  1. DrSueCancerVet (drsuecancervet.com)
  2. published exciting results (umn.edu)
  3. recent study (hindawi.com)
  4. American College of Veterinary Internal Medicine (acvim.org)
  5. American College of Veterinary Surgeons (acvs.org)
  6. Hemangiosarcoma in Dogs (csuanimalcancercenter.org)
  7. AKC Rx (akcpetrx.com)
  8. Hemangiosarcoma is the cause of approximately 300,000 dog deaths in the U.S. annually (akcchf.org)
  9. Hemangiosarcoma is known as a “silent killer” (aaha.org)
  10. even large hemangiosarcoma tumors may show no signs (akcchf.org)
  11. most significantly mutated gene to be tumor suppressor TP53 (nih.gov)
  12. Shine On Project (umn.edu)
  13. Tufts Cummings School of Veterinary Medicine (tufts.edu)
  14. grant from the AKC Canine Health Foundation (akcchf.org)
  15. The Role Of Neutering In Cancer Development. (ncsu.edu)
  16. Cardiac tumors in dogs: 1982-1995 (nih.gov)
  17. Neutering is associated with developing hemangiosarcoma in dogs in the Veterinary Medical Database: An age and time-period matched case-control study (1964-2003) (nih.gov)
  18. Prevalence, distribution, and clinical characteristics of hemangiosarcoma-associated skeletal muscle metastases in 61 dogs: A whole body computed tomographic study (wiley.com)
  19. Hemangiosarcoma in a Dog: Unusual Presentation and Increased Survival Using a Complementary/Holistic Approach Combined with Metronomic Chemotherapy (nih.gov)
  20. Single Agent Polysaccharopeptide Delays Metastases and Improves Survival in Naturally Occurring Hemangiosarcoma (nih.gov)
  21. In vitro effects of Yunnan Baiyao on canine hemangiosarcoma cell lines (wiley.com)
  22. Hemangiosarcoma in Dogs: Diagnosis & Treatment Options (ethosvet.com)

Shawna Welch

Writer

Shawna Welch is a versatile and engaging writer with a passion for exploring complex topics in an approachable way. With a keen interest in animal behavior, Shawna has developed a niche expertise in canine behavioral issues, shedding light on common problems and offering actionable advice for pet owners. Her writing style is characterized by clarity, empathy, and a commitment to accuracy, making her a trusted voice in the field.