Dog Metabolic Diseases: Causes, Symptoms, and Prevention

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Posted Nov 3, 2024

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Dog metabolic diseases can be a real challenge for pet owners. Hypothyroidism is one of the most common metabolic diseases in dogs, affecting up to 1 in 200 dogs.

Dogs with hypothyroidism often experience weight gain, dry skin, and a dull coat. In severe cases, it can lead to heart problems and reproductive issues.

Regular check-ups with your veterinarian can help identify potential issues early on. They will perform blood tests to monitor your dog's thyroid hormone levels and adjust treatment as needed.

What Is Dog Metabolic Disease?

Dog metabolic diseases are a group of conditions that affect a dog's ability to regulate its blood sugar levels and other metabolic processes.

Diabetes in dogs, also known as canine diabetes, is a chronic metabolic disorder that affects a dog's ability to regulate its blood sugar levels. This condition can occur in dogs of any age, but it occurs most frequently in middle-aged to older dogs.

Here's an interesting read: Canine Diabetes Glucose Levels

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Increased thirst and urination, along with weight loss and increased appetite, are classic signs of diabetes in dogs. These symptoms can be a major red flag for dog owners, and it's essential to consult with a vet if you notice any of these changes in your furry friend.

Insulin therapy and diet are the cornerstones of therapy for dogs with diabetes. Your vet may recommend insulin injections that should be given throughout the rest of your dog's life.

Feeding your dog correctly can help decrease stress on the metabolic system, allowing it to function optimally. This can put your dog in the best possible position to fight against life-threatening metabolic diseases, such as diabetes.

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Causes and Risk Factors

Some breeds are genetically predisposed to diabetes, such as Pugs, Poodles, Beagles, Daschunds, and Labrador Retrievers.

Obesity is a significant risk factor for diabetes in dogs, as excess body fat can lead to insulin resistance, making it hard for the body to use insulin effectively.

Genetic predisposition can't be changed, but obesity can be managed through a healthy diet and regular exercise.

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Causes of

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Diabetes in dogs can be caused by a range of conditions, such as obesity, which is a major risk factor for canine diabetes.

Obesity is often caused by overfeeding, lack of exercise, or genetics.

A sedentary lifestyle can also contribute to weight gain and obesity.

Genetic predisposition can play a role in the development of diabetes in certain breeds.

Genetic Predisposition

Genetic Predisposition plays a significant role in canine diabetes. Some breeds are more prone to developing the condition due to their genetic makeup.

Certain breeds are at a higher risk of developing genetic storage diseases, which can increase their likelihood of developing diabetes. For example, Pugs, Poodles, Beagles, Daschunds, and Labrador Retrievers are more prone to diabetes.

Genetic storage diseases can also lead to other health issues, such as lameness or anemia. Breeds like Miniature Pinschers, Mixed-breed dogs, and Plott Hounds are more susceptible to mucopolysaccharidosis, which can cause lameness.

Here's a list of breeds prone to genetic storage diseases that can increase their risk of diabetes:

  • Border Collies, Chihuahuas, Cocker Spaniels, Dachshunds, English Setters, Salukis (Ceroid lipofuscinosis)
  • Beagle crosses, German Shorthaired Pointers, Japanese Spaniels (Gangliosidoses)
  • Beagles, Bluetick Hounds, Cairn Terriers, Poodles, West Highland White Terriers (Globoid cell leukodystrophy)
  • Australian Silky Terriers, Dalmatians (Glucocerebrosidosis)
  • Silky Terriers (Glycogenosis)
  • Miniature Pinschers, Mixed-breed dogs, Plott Hounds (Mucopolysaccharidosis)
  • American Cocker Spaniels, English Springer Spaniels (Phosphofructokinase deficiency)
  • Basenjis, Beagles, Cairn Terriers, West Highland White Terriers (Pyruvate kinase deficiency)
  • German Shepherds, Poodles (Sphingomyelinosis)

Obesity

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Obesity is a significant risk factor for diabetes in dogs. It can lead to insulin resistance, making it harder for the body to use insulin effectively.

Excess body fat can cover the ribs, making them difficult to feel. This is a key indicator of an overweight dog.

To check your dog's weight, you can use the Body Condition Score (BSC) chart. This chart helps you assess your dog's body condition by evaluating their ribs, abs, and waistline.

Here's a quick rundown of what to look for:

  • Feel your dog's ribs: You should be able to feel them when pressing gently, but not with excessive fat covering them.
  • Check your dog's abs: Look for a tapered appearance where the chest transitions to the belly.
  • Look at your dog's waistline: A slightly tapered-in waistline is a good indicator of a healthy weight.

A BSC of 6-9 indicates that your dog may be overweight or obese. It's essential to consult with your vet about the best plan to help your pet achieve a healthy weight.

Steroid Use

Steroid Use can significantly impact a dog's health. Long-term use of medications containing corticosteroids can increase the risk for canine diabetes.

Symptoms and Diagnosis

Symptoms of metabolic diseases in dogs can be subtle, but it's essential to catch them early. If your dog is drinking more water than usual, it could be a sign of trouble brewing.

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An increase in appetite can also be a warning sign. Your dog may be eating more than usual, or they may be showing a decrease in appetite.

Physical changes, such as weight loss or gain, can also indicate a metabolic issue. Keep an eye out for any changes in your dog's physical appearance.

Diagnosing metabolic diseases in dogs usually involves a series of tests and examinations. Your veterinarian may perform blood tests to check for excessive glucose levels, high liver and kidney enzymes, and electrolyte imbalances.

A urinalysis can also be conducted to test for glucosuria, which is glucose in the urine. Your veterinarian may also perform a fructosamine test, which provides information about your dog's blood sugar control over the last two to three weeks.

Here are some potential health issues that can arise if left untreated:

  • Dehydration
  • Pancreatitis
  • Fatty liver disease
  • Urinary tract infections
  • Diabetic neuropathy – weakness, unsteadiness, seizures, coma
  • Kidney failure
  • Ketoacidosis

Specific Diseases

Some dog breeds are more prone to genetic storage diseases, which can affect their quality of life and lifespan. Border Collies, Chihuahuas, Cocker Spaniels, Dachshunds, English Setters, and Salukis are susceptible to ceroid lipofuscinosis.

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Globoid cell leukodystrophy, also known as Krabbe's disease, affects Beagles, Bluetick Hounds, Cairn Terriers, Poodles, and West Highland White Terriers. This disease can cause severe neurological symptoms, including seizures and loss of coordination.

The following breeds are prone to various genetic storage diseases:

Mellitus

Diabetes mellitus is a common metabolic disorder in dogs that occurs when the pancreas doesn't produce enough insulin or the body doesn't react properly to insulin. This hormone regulates blood sugar levels, and without enough of it, blood sugar rises.

Symptoms of diabetes mellitus in dogs include frequent drinking and urination, weight loss despite a good appetite, and weakness and tiredness. Vomiting and diarrhea, poor wound healing, and cataracts are also possible.

Normal blood sugar levels in healthy dogs range from 80 to 120 milligrams per decilitre (mg/dl). Most dogs can handle a spike up to 250 mg without any major side effects.

If your dog is showing signs of a metabolic or endocrine disease, such as an increase in water intake or a change in appetite, it's essential to bring it up with your vet. They may run some basic blood work to diagnose the issue.

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Here's a quick rundown of some common symptoms of diabetes mellitus in dogs:

  • Frequent drinking and urination
  • Weight loss despite a good appetite
  • Weakness and tiredness
  • Vomiting and diarrhea
  • Poor wound healing
  • Cataracts

Keep in mind that some dogs may experience a temporary spike in glucose levels after a meal, but this is usually not a cause for concern.

Hyperadrenocorticism (Cushing's Disease)

Hyperadrenocorticism, also known as Cushing's disease, is a metabolic and endocrine disease caused by the pituitary gland producing too much adrenocorticotropic stimulating hormone.

This hormone stimulates the adrenal gland to excessively produce glucocorticoids, a stress hormone that has many metabolic effects, including the breakdown of muscle.

The symptoms of Cushing's disease in dogs can be similar to other metabolic problems, including increased thirst and urination.

Some other signs of Cushing's disease include poor coat with hair loss, skin problems, panting, and increased appetite and weight gain.

Cushing's disease is usually treated with medication, and it's essential to work closely with a veterinarian to find the right treatment plan for your dog.

Here are some common symptoms of Cushing's disease in dogs:

  • Frequent drinking and urination
  • Thin skin and hair loss
  • Big belly and muscle wasting
  • Increased appetite and thirst
  • Susceptibility to infections and poor wound healing
  • Nervousness and restlessness

Hypothyroidism

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Hypothyroidism can cause a sluggish metabolism in dogs, leading to weight gain and poor coat quality.

Dogs with hypothyroidism often lose energy and develop dry skin.

Their coat quality can decline significantly, making them look dull and unhealthy.

Luckily, hypothyroidism can be treated with thyroid hormone supplementation.

With proper treatment, dogs can regain their energy and enjoy a healthy, shiny coat once again.

Hypoadrenocorticism (Addison's Disease)

Hypoadrenocorticism, also known as Addison's disease, is a condition where dogs lack one or two types of hormones.

This disease can cause chronic and intermittent vomiting, as well as lethargy in affected dogs.

Even small stressors, such as boarding or a simple infection, can become life-threatening for these dogs.

Addison's disease tends to be diagnosed in young dogs, and it can be tricky to get a firm diagnosis, sometimes requiring special testing.

Treatment for Addison's disease involves medication to replace the missing hormones, and it's essential to remember that this is a lifelong commitment.

Sources

  1. Metabolic disorders in dogs - fellow.dog (fellow.dog)
  2. Diabetes in Dogs: Causes, Symptoms, and Treatment (bettervet.com)
  3. How to spot metabolic diseases in dogs (fetchpet.com)
  4. Introduction to Metabolic Disorders of Dogs - Dog Owners (merckvetmanual.com)
  5. source (dogsnaturallymagazine.com)
  6. obesity (petobesityprevention.org)
  7. metabolic disease (nih.gov)
  8. source (nih.gov)

Jenna Koch

Senior Writer

Jenna Koch is a versatile and passionate writer with a keen interest in exploring various topics. Her writing career has taken off with a focus on informative and engaging content, covering a range of subjects that spark curiosity and interest in readers. Jenna's expertise lies in crafting well-researched and accessible articles that cater to diverse audiences.