Understanding Dog Blood Work Cancer: Causes, Diagnosis, and Prognosis

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Posted Nov 2, 2024

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Dog blood work cancer can be a scary diagnosis, but understanding the basics can help you navigate the process. Cancer can develop in any part of the body, including the blood vessels, spleen, and bone marrow.

The most common types of blood cancer in dogs are lymphoma, leukemia, and multiple myeloma. These conditions can be caused by genetic mutations, environmental factors, or a combination of both.

What Causes It?

Genetics and environmental factors may play a role in the development of osteosarcoma in dogs. Certain large and giant dog breeds, such as German Shepherds, Saint Bernards, Rottweilers, and Greyhounds, may have an increased genetic risk for developing this type of cancer.

Osteosarcoma can also develop in bones that have experienced previous trauma, including radiation therapy sites, previously healed fractures, and previous bone infections (osteomyelitis).

Exposure to certain toxins can increase the likelihood of a dog developing osteosarcoma. Regular check-ups with your veterinarian are highly recommended to catch any potential signs or symptoms early on.

Symptoms and Diagnosis

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Symptoms of dog cancer can be subtle, but there are some common signs to look out for. These include lameness that doesn't go away, swelling of the affected bone, and difficulty eating if a tumor affects the jaw.

Loss of appetite, lethargy, and unexplained weight loss are also potential warning signs. You should also pay attention to any lumps or bumps you may find on your dog's body while grooming or petting them.

Here are some common symptoms of dog cancer to watch out for:

  • Swelling
  • Sores that don’t heal
  • Strong odor
  • Bleeding or discharge
  • Unexplained weight loss
  • Appetite loss
  • Difficulty or pain when walking, stiffness or lameness
  • Lumps or pumps below the skin
  • Challenges when swallowing or eating

If you notice any of these symptoms, it's essential to schedule an appointment with your vet immediately. They may perform a biopsy or other diagnostic test to determine the best course of action.

Dog Health Symptoms

Osteosarcoma, a type of bone cancer, can occur in any bone, but in dogs, most tumors appear in the front limbs near the shoulder, wrist, and knee.

The symptoms of osteosarcoma in dogs can be subtle, but may include lameness that doesn't go away and swelling of the affected bone.

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Swelling or a mass is often the first sign of a tumor in the skull, jaw, or ribs.

Difficulty eating if a tumor affects the jaw is another possible symptom.

Neurologic signs, such as seizures or a wobbly gait, can occur with skull or spinal/vertebral tumors.

Breathing difficulties or lameness can occur with rib tumors.

Loss of appetite and lethargy are common symptoms of many cancers, including osteosarcoma.

Sores that don't heal are a sign that your dog's immune system isn't functioning properly, or is busy combating another infection.

Bleeding or discharge can also be a symptom of cancer.

Loss of appetite is a sign that something isn't right with your dog.

Unexplained weight loss is another warning sign of cancer in dogs.

Strong odor can be a sign of a tumor in the mouth or ears.

Swelling is a common symptom of many cancers, including osteosarcoma.

Lumps or bumps beneath the skin can be a sign of cancer.

Lethargy, depression, disinterest in exercise can be symptoms of cancer.

Here's an interesting read: Canine Transmissible Venereal Tumor

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Difficult or painful breathing or coughing can be a sign of throat and neck cancers.

Straining when going to the bathroom can be a sign of cancer.

Challenges when eating or swallowing can be a symptom of throat and neck cancers.

Pain or difficulty walking, lameness or stiffness can be a sign of bone cancer.

Here are some common symptoms of cancer in dogs:

  • Sores that don't heal
  • Bleeding or discharge
  • Loss of appetite
  • Unexplained weight loss
  • Strong odor
  • Swelling
  • Lumps or bumps beneath the skin
  • Lethargy, depression, disinterest in exercise
  • Difficult or painful breathing or coughing
  • Straining when going to the bathroom
  • Challenges when eating or swallowing
  • Pain or difficulty walking, lameness or stiffness

It's essential to consult with a veterinarian if you notice any of these symptoms in your dog.

How Is Diagnosed?

In many cases, a veterinarian will start by taking an X-ray to rule out other causes of lameness and identify any problem areas.

A biopsy is often necessary to obtain a definitive diagnosis and determine the best treatment plan for your dog. This involves taking a sample of the tumor for further analysis.

Over 90% of dogs have already metastasized by the time of diagnosis, and osteosarcoma most commonly spreads to the lungs. So, it's essential to get your dog checked out as soon as possible.

Chest X-rays or a computed tomography (CT) scan, blood tests, and a urinalysis will usually be performed to assess your dog's overall health and determine if cancer has spread.

Diagnosis and Staging

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Your veterinarian will first take an X-ray to rule out other causes of lameness and perform a physical and orthopedic examination.

In over 90% of dogs, the tumor will have already metastasized at the time of diagnosis, and osteosarcoma most commonly spreads to the lungs.

A biopsy will be taken to obtain a definitive diagnosis and determine the best treatment plan for your dog.

Chest X-rays or a computed tomography (CT) scan, blood tests, and a urinalysis will usually be performed to assess your dog's overall health and determine if cancer has spread.

An advanced CT is often recommended for osteosarcoma tumors of the limbs, providing more detailed imagery of the tumor.

Your veterinarian will palpate your dog to feel for any bumps or lumps, and perform a biopsy or other diagnostic test to determine if your dog has cancer.

The vet will send the biopsy to a lab for testing, and recommend the best treatment options based on the results.

In order to determine the best treatment plan, your veterinarian will need to know if the cancer has spread, which is why they will perform additional diagnostics like chest X-rays or a CT scan.

Treatment and Prognosis

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Osteosarcoma in dogs has a variety of treatments, including amputation, limb-sparing surgery, and stereotactic radiation.

The prognosis for pets with osteosarcoma depends on the severity and spread of the disease and on the treatment you choose.

Dogs with limb osteosarcoma that receive stereotactic radiation and chemotherapy have a median survival time of about one year.

Up to 16–28% of dogs are alive at two years after receiving this treatment.

Amputation alone has a median survival time of about three months, but it's still an option for some dogs.

Life Expectancy and Prognosis

Dogs with limb osteosarcoma that receive SRS and chemotherapy have a median survival time of about one year.

The prognosis for pets with osteosarcoma depends on the severity and spread of the disease and on the treatment you choose.

Up to 16–28% of dogs are alive at two years after receiving SRS and chemotherapy.

Dogs with amputation alone have a median survival time of about three months.

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Palliative treatment aims to make your pet more comfortable but doesn’t provide a cure, and can include conventional radiation therapy and drugs to reduce pain.

A 2012 study showed that an extract of a medicinal mushroom, Coriolus versicolor, can extend the lives of dogs with hemangiosarcoma, with no side effects and a relatively low cost.

After Radiation Treatment

After radiation treatment, your dog's recovery process will vary depending on their individual circumstances.

The most common side effects include a sunburn-like effect on the skin in the treatment field, and fur loss in that area with white fur regrowth.

It's crucial to keep your dog quiet on the affected limb, avoiding activities like running, jumping, or excitement, as there's an increased risk for fracture.

Your dog will need plenty of rest and high-quality nutrition to aid in the healing process.

Pain medications may be prescribed by your veterinarian if needed, so be sure to follow their instructions carefully.

Early detection of recurrence or progression of the cancer, including metastasis, is critical for ensuring successful treatment outcomes.

Types of Cancer

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Dogs can get many of the same types of cancer that can infect humans, and some symptoms may be similar. Cancer in dogs can be a serious illness, but knowing the signs and symptoms can help you spot it early.

Some common types of cancer in dogs include hemangiosarcoma, lymphoma, and osteosarcoma. Hemangiosarcoma is a type of cancer that can grow quite large and is often found in the spleen, but may grow anywhere blood vessels are present.

The most common types of lymphoma in dogs are alimentary, multicentric, extranodal, and mediastinal lymphoma. Osteosarcoma is a type of bone cancer that is common in dogs, especially larger breeds.

Here are some common types of cancer in dogs:

  • Fibrosarcomas
  • Infiltrative Lipomas
  • Mammary Tumors
  • Mast Cell Tumors
  • Osteosarcomas
  • Soft-Tissue Sarcomas

Breeds Predisposed?

If you're the owner of a Golden Retriever, German Shepherd, Portuguese Water Dog, Boxer, or Skye Terrier, be aware that these breeds are commonly affected by hemangiosarcoma cancer.

These breeds are more prone to hemangiosarcoma, a serious cancer that can be life-threatening, so it's essential to stay vigilant about your dog's energy levels and skin.

Golden Retrievers, in particular, are at high risk, so regular check-ups with your vet are crucial to catch any potential issues early.

Brain Tumors

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Brain Tumors can be a serious concern for our furry friends. Gliomas in dogs are a type of brain tumor that can be aggressive and difficult to treat.

These tumors can grow quickly and spread to other parts of the brain. Meningiomas in dogs, on the other hand, are usually slow-growing and may not cause symptoms until they are quite large.

Pituitary Tumors in Dogs can affect the production of hormones in the body, leading to a range of symptoms.

Here are some common types of brain tumors found in dogs:

  • Gliomas
  • Meningiomas
  • Pituitary Tumors

Extremity Tumors

Extremity Tumors in Dogs can be a serious concern. Fibrosarcomas are a type of soft-tissue sarcoma that can occur in a dog's limbs, often requiring surgical removal.

Some common types of extremity tumors in dogs include Fibrosarcomas, Infiltrative Lipomas, and Mast Cell Tumors. These tumors can be painful and disfiguring, but early detection and treatment can make a big difference.

For more insights, see: Canine Brain Cancer Symptoms

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Osteosarcomas are a type of bone cancer that can occur in a dog's limbs, often causing pain and discomfort. If left untreated, Osteosarcomas can be fatal.

Here are some common types of extremity tumors in dogs:

  • Fibrosarcomas in Dogs
  • Infiltrative Lipomas in Dogs
  • Mast Cell Tumors in Dogs
  • Osteosarcomas in Dogs
  • Soft-Tissue Sarcomas in Dogs

Lymphoma/Lymphosarcoma

Lymphoma/Lymphosarcoma is a very common form of cancer in dogs, and there are more than 30 categories of lymphoma that can develop in their bodies.

Lymphoma is a generic term used by vets to describe a group of cancers that stem from a type of white blood cell called lymphocytes that help the immune system to fight off infection.

The most common types of lymphoma in dogs are multicentric, alimentary, mediastinal, and extranodal lymphoma.

Signs of lymphoma in dogs include swelling under the jaw, in front of the shoulders, and behind the knees. Lethargy, decreased appetite, and coughing may also accompany swollen lymph nodes.

Treatment for lymphoma typically involves chemotherapy to help manage the cancer and improve your dog's quality of life.

Here are the common types of lymphoma in dogs:

Frequently Asked Questions

Does cancer show in blood work for dogs?

Blood work for dogs can indicate health problems, but it doesn't directly diagnose cancer. Changes in white blood cell, red blood cell, and organ function counts may suggest cancer, but further testing is needed for a definitive diagnosis.

What is the most aggressive dog cancer?

Hemangiosarcoma is a highly aggressive form of dog cancer that requires immediate attention. It's a rapidly growing tumor that can spread to vital organs if not treated promptly.

How much does the OncoK9 test cost?

The OncoK9 test costs $599. This price tag was not mentioned in the initial joint press release with Petco in May 2021.

Bernard Prohaska

Senior Writer

Bernard Prohaska is a seasoned writer with a passion for crafting engaging and informative content. His writing career spans a wide range of topics, but he has developed a particular expertise in pet care and animal health. With a keen interest in reproductive health in canines, Bernard has written extensively on the subject, providing valuable insights and advice to pet owners.